Table 1

The appearance and clearance of HSV-1 antigen positive cells and 'focal' areas of viral antigen positive cells throughout the brains of inbred strains of mice

Mouse straina

Initial appearance of viral

antigen positive

cells throughout the brains

Clearance of viral antigen throughout the brain (days PI)


RTNBSTb

BSTc

CBd

CRe (days PI)


BL/6

3

-

-

-

12


BALB/c

3

3

6

7

18


SJL/J

6

6

7

8

21


A/J

3

3

6

7

21


PL/J

3

3

5

6

21


Mouse straina ext

Initial appearance of 'focal' areas of viral antigen positive cells throughout the brain

Clearance of viral antigen throughout the brain (days PI)


RTNBSTa

BSTb

CBc

CRd (days PI)


BL/6

-

-

-

-

12


BALB/c

5

-

-

-

18


SJL/J

9

9

12

15

21


A/J

5

5

9

12

21


PL/J

5

5

6

9

21


aTen-12 week ♀ inbred mice were infected with HSV-1 strain 2 via the oral mucosa. Three mice of each strain were examined every 3 days or as necessary from Day 0 through 30 PI.

bRoots of the trigeminal nerve in the brainstem

cBrainstem

dCerebellum

eCerebral hemispheres

Kastrukoff et al. Herpesviridae 2012 3:4   doi:10.1186/2042-4280-3-4

Open Data