Table 4

Quantitative analysis of immature and mature germ cells in HCMV-infected human testis organotypic culture

Germ cells

Organotypic culture in vitro, days


7

14


Uninfected

HCMV-infected

P-value

Uninfected

HCMV-infected

P-value


Spermatogonia

100a

53,8

<0.001b

82,2

36,8

<0.001


Spermatocytes

100

38,9

<0.001

51,5

18,7

<0.001


Round spermatids

104

37,7

<0.001

70,4

27,6

<0.001


Elongated spermatids

96

57,7

<0.001

65,7

42,5

<0.05


Spermatozoa

106,3

100

>0.05

106,3

100

>0.05


a - mean quantity of cells, %; quantity of cells before introduction in culture was taken for 100%;

b - Student's paired t-test.

Naumenko et al. Herpesviridae 2011 2:7   doi:10.1186/2042-4280-2-7

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